Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782702 | 1.00 | UCHL1 (0.35) | UCHL1PARP1LIPELPLLIPG | |
| SCHEMBL19776254 | 0.83 | UCHL1 (0.34) | UCHL1LIPE | |
| SCHEMBL29481814 | 0.83 | UCHL1 (0.34) | UCHL1LIPE | |
| SCHEMBL29481822 | 0.80 | UCHL1 (0.35) | UCHL1LIPE | |
| SCHEMBL19776055 | 0.80 | UCHL1 (0.35) | UCHL1LIPE | |
| SCHEMBL30189867 | 0.79 | EGFR (0.35) | LIPE | |
| SCHEMBL19783805 | 0.79 | EGFR (0.35) | LIPE | |
| SCHEMBL21395408 | 0.77 | BACE1 (0.33) | LIPE | |
| SCHEMBL30189937 | 0.77 | BACE1 (0.33) | LIPE | |
| SCHEMBL19776338 | 0.76 | CTSD (0.34) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |