Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21379306 | 1.00 | LMNA (0.40) | LMNAACACBF2RL3MEN1KMT2A | |
| SCHEMBL21379432 | 0.83 | CYP1A2 (0.41) | LMNAMEN1KMT2AMAPK1KDM4E | |
| SCHEMBL21379552 | 0.78 | NTRK1 (0.32) | ACACB | |
| SCHEMBL22341910 | 0.76 | ABL1 (0.39) | ACACBKMT2AALDH1A1P4HTMPTPN1 | |
| SCHEMBL21379604 | 0.76 | ABL1 (0.39) | ACACBKMT2AALDH1A1P4HTMPTPN1 | |
| SCHEMBL21379601 | 0.76 | ABL1 (0.39) | ACACBKMT2AALDH1A1P4HTMPTPN1 | |
| SCHEMBL15880582 | 0.75 | KMT2A (0.41) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21407998 | 0.75 | ABL1 (0.40) | LMNAF2RL3KMT2AALDH1A1P4HTM | |
| SCHEMBL28941087 | 0.74 | DGAT1 (0.36) | MEN1KMT2AP4HTMHDAC6 | |
| SCHEMBL21379329 | 0.74 | APLNR (0.38) | LMNAKDM4EP4HTMPTPN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |