SCHEMBL3019034

SCHEMBL3019034

C[Si](C)(C)N(CCCl)[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
LMNA P02545 2/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
HBB P68871 1/20 0.40
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4188648 0.81 TSHR (0.33) MAPTLMNATP53TSHRHTT
SCHEMBL1464789 0.73 MAPT (0.42) MAPTLMNATP53TSHRHTT
SCHEMBL15275272 0.72
SCHEMBL5076227 0.71
SCHEMBL906672 0.69
SCHEMBL5079268 0.67 MAPT (0.36) MAPTLMNATP53TSHRHTT
SCHEMBL4644466 0.67
SCHEMBL9491694 0.67
SCHEMBL3480685 0.67
SCHEMBL2798975 0.67 CA12 (0.44) MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362216-A Application of Picer type PNP manganese complex catalyst 河南农业大学 2024-01-09 CN disclosed
CN-115785091-A Method for catalytically synthesizing tetrahydro-beta-carboline compound by utilizing PNP type pincerlike manganese catalyst 邵秀兰 2023-03-14 CN disclosed
CN-112830449-B Reversible liquid organic hydrogen storage method based on manganese catalytic hydrogenation and dehydrogenation reaction 清华大学 2022-09-27 CN disclosed
US-8658825-B2 Method for the preparation of aminophosphine ligands and their use in metal catalysts KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2014-02-25 US disclosed
US-8658825-B2 Method for the preparation of aminophosphine ligands and their use in metal catalysts KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2014-02-25 US disclosed
US-8658825-B2 Method for the preparation of aminophosphine ligands and their use in metal catalysts KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2014-02-25 US disclosed
US-20100204514-A1 METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2010-08-12 US disclosed
US-20100204514-A1 METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2010-08-12 US disclosed
US-20100204514-A1 METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2010-08-12 US disclosed
EP-2167515-A1 METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS Kanata Chemical Technologies Inc. (CA) 2010-03-31 EP disclosed
WO-2008148202-A1 METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2008-12-11 WO disclosed
EP-1245585-B1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORP (JP) 2008-05-21 EP disclosed
US-6838538-B2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20030100683-A1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2003-05-29 US disclosed
EP-1245585-A2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR Corporation (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204514-A1 METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS PNISR, PRMT9, PRMT8 MAPT 4425/4885LMNA 1794/4885TP53 2520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.