Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 16/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923666 | 0.81 | EGLN1 (0.51) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24916482 | 0.81 | EGLN1 (0.51) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24886246 | 0.76 | WDR5 (0.49) | WDR5KMT2A | |
| SCHEMBL24886125 | 0.75 | WDR5 (0.43) | WDR5KMT2AALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL27232914 | 0.72 | WDR5 (0.44) | WDR5KMT2A | |
| SCHEMBL29923808 | 0.71 | PARP1 (0.33) | WDR5KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL24886065 | 0.70 | PTGER4 (0.47) | WDR5PTGER4PTGER2ALDH1A1PKM | |
| SCHEMBL24916486 | 0.70 | PTGDR2 (0.34) | — | |
| SCHEMBL29923758 | 0.70 | PTGDR2 (0.34) | — | |
| SCHEMBL27167349 | 0.70 | NOTUM (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012362-A1 | WDR5 INHIBITORS AND MODULATORS | WDR5, WDR1, WDR77 | WDR5 1/4885PTGER4 4539/4885PTGER2 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.