Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22112025 | 1.00 | CA9 (0.39) | CA9CA12CA1CA3CA6 | |
| SCHEMBL1494587 | 0.80 | GAA (0.38) | CA9CA12CA1GAAMAPT | |
| SCHEMBL6634785 | 0.80 | CA9 (0.50) | CA9CA12CA1CA3CA6 | |
| SCHEMBL4962657 | 0.79 | CA6 (0.44) | CA9CA12CA1CA3CA6 | |
| SCHEMBL29671237 | 0.76 | ALOX15 (0.35) | CA1CA6ALOX15MAPTCYP3A4 | |
| SCHEMBL29671197 | 0.76 | ALOX15 (0.35) | CA1CA6ALOX15MAPTCYP3A4 | |
| SCHEMBL23899974 | 0.75 | CA9 (0.36) | CA9CA12CA1CA3CA6 | |
| SCHEMBL22119947 | 0.75 | TSHR (0.41) | CA9CA1CA3CA6CA5A | |
| SCHEMBL22690036 | 0.75 | ACHE (0.40) | CA9CA12CA1CA3CA6 | |
| SCHEMBL20241670 | 0.75 | SELL (0.46) | CA1CA6GAAALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |