SCHEMBL30193091

SCHEMBL30193091

NC(=O)c1cc(CO)ccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.50
CYP4F2 P78329 3/20 0.45
CYP4A11 Q02928 2/20 0.45
PLAU P00749 1/20 0.44
ADORA3 P0DMS8 1/20 0.42
TSHR P16473 1/20 0.42
MC4R P32245 1/20 0.42
ADRA1A P35348 1/20 0.42
MC3R P41968 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328151 1.00 RECQL (0.50) RECQLCYP4F2CYP4A11PLAUADORA3
SCHEMBL2176535 0.85 LOXL2 (0.56) CYP4F2CYP4A11ADORA3TSHRMC4R
SCHEMBL20377228 0.85 CYP4F2 (0.45) CYP4F2CYP4A11ADORA3TSHRMC4R
SCHEMBL1388918 0.84 GRM2 (0.46) CYP4F2CYP4A11ADORA3TSHRMC4R
Hydrochloric Acid SCHEMBL5013437 0.83 LOXL2 (0.55) CYP4F2CYP4A11ADORA3TSHRMC4R
SCHEMBL2642856 0.83 CYP4F2 (0.44) CYP4F2CYP4A11ADORA3TSHRMC4R
SCHEMBL2677778 0.83 SMYD3 (0.54) CYP4F2CYP4A11ADORA3TSHRMC4R
SCHEMBL19211551 0.83 CYP4F2 (0.44) RECQLCYP4F2CYP4A11ADORA3TSHR
SCHEMBL4016509 0.83 CYP4F2 (0.44) CYP4F2CYP4A11ADORA3TSHRMC4R
SCHEMBL4302305 0.83 CYP4F2 (0.43) RECQLCYP4F2CYP4A11PLAULOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 US disclosed
US-11931348-B2 Methods of treating elevated plasma cholesterol Montréal Heart Institute (CA) 2024-03-19 US disclosed
CN-112638477-B Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication 共晶制药公司 2024-01-26 CN disclosed
US-20230088095-A1 METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL Montréal Heart Institute (CA) 2023-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC RECQL 2302/4885CYP4F2 3529/4885CYP4A11 3921/4885
US-11931348-B2 Methods of treating elevated plasma cholesterol CETP, LDLR, APOB RECQL 2203/4885CYP4F2 171/4885CYP4A11 76/4885
US-20230088095-A1 METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL CETP, LDLR, APOB RECQL 2203/4885CYP4F2 171/4885CYP4A11 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.