Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 13/20 | 0.56 |
| ▸ | LOX | P28300 | 3/20 | 0.50 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5013437 | 0.98 | LOXL2 (0.55) | LOXL2LOXLOXL3CYP4F2CYP4A11 | |
| SCHEMBL9339179 | 0.85 | LOXL2 (0.44) | LOXL2CYP4F2CYP4A11ADORA3TSHR | |
| SCHEMBL2328151 | 0.85 | RECQL (0.50) | LOXL2CYP4F2CYP4A11ADORA3TSHR | |
| SCHEMBL30193091 | 0.85 | RECQL (0.50) | LOXL2CYP4F2CYP4A11ADORA3TSHR | |
| SCHEMBL20377228 | 0.85 | CYP4F2 (0.45) | LOXL2CYP4F2CYP4A11ADORA3TSHR | |
| SCHEMBL2880084 | 0.85 | LOXL2 (0.57) | LOXL2LOXLOXL3CYP4F2CYP4A11 | |
| SCHEMBL4016509 | 0.83 | CYP4F2 (0.44) | LOXL2CYP4F2CYP4A11ADORA3TSHR | |
| SCHEMBL2643691 | 0.83 | LOXL2 (0.55) | LOXL2LOXLOXL3GABRPGABRD | |
| SCHEMBL19211551 | 0.83 | CYP4F2 (0.44) | LOXL2CYP4F2CYP4A11ADORA3TSHR | |
| SCHEMBL2677778 | 0.83 | SMYD3 (0.54) | LOXL2CYP4F2CYP4A11ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312316-A1 | NOVEL COMPOUNDS | BIOTICA TECHNOLOGY LIMITED (GB) | 2009-12-17 | — | — | US | claimed |
| EP-2023915-A2 | BORRELIDIN DERIVATIVES AS ANTIPROLIFERATIVE AGENTS AND ANGIOGENESIS INHIBITORS | Biotica Technology Limited (GB) | 2009-02-18 | — | — | EP | claimed |
| WO-2007135078-A2 | BORRELIDIN DERIVATIVES AS ANTIPROLIFERATIVE AGENTS AND ANGIOGENESIS INHIBITORS | BIOTICA TECHNOLOGY LIMITED (GB) | 2007-11-29 | — | — | WO | claimed |
| US-20040157834-A1 | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor | PFIZER INC | 2004-08-12 | — | — | US | claimed |
| US-6720330-B2 | INCREASING SECRETION OF GROWTH HORMONE, GASTRIN, OR GLUCAGON IN A MAMMAL; INHIBITING THE BINDING OF SOMATOSTATIN TO AN SST2 RECEPTOR | PFIZER INC. | 2004-04-13 | — | — | US | claimed |
| US-20020091125-A1 | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor | HAY BRUCE A (US) | 2002-07-11 | — | — | US | claimed |
| US-5387595-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1995-02-07 | — | — | US | claimed |
| WO-1994004487-A1 | ALICYCLIC COMPOUNDS AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-03-03 | — | — | WO | claimed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-2285783-B1 | INDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2014-05-21 | — | — | EP | disclosed |
| EP-2050446-B1 | SULFONAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2050446-B1 | SULFONAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-20040157834-A1 | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor | PFIZER INC | 2004-08-12 | — | — | US | disclosed |
| US-6720330-B2 | INCREASING SECRETION OF GROWTH HORMONE, GASTRIN, OR GLUCAGON IN A MAMMAL; INHIBITING THE BINDING OF SOMATOSTATIN TO AN SST2 RECEPTOR | PFIZER INC. | 2004-04-13 | — | — | US | disclosed |
| US-20020091125-A1 | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor | HAY BRUCE A (US) | 2002-07-11 | — | — | US | disclosed |
| US-5387595-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994004487-A1 | ALICYCLIC COMPOUNDS AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312316-A1 | NOVEL COMPOUNDS | CD22, ALDH1A2, BCAP31 | LOXL2 2999/4885LOX 3160/4885LOXL3 2456/4885 |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | LOXL2 2232/4885LOX 1831/4885LOXL3 2283/4885 |
| US-20040157834-A1 | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor | SSTR2, GHSR, SSTR1 | LOXL2 3186/4885LOX 3542/4885LOXL3 3410/4885 |
| US-20020091125-A1 | Somatostatin antagonists and agonists that act at the SST subtype 2 receptor | SSTR2, GHSR, SSTR1 | LOXL2 3246/4885LOX 3606/4885LOXL3 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.