Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227813 | 0.79 | S1PR3 (0.39) | LMNAS1PR3GAAKDM4EMEN1 | |
| SCHEMBL30195140 | 0.74 | LMNA (0.55) | LMNAPOLBGAAMEN1KMT2A | |
| SCHEMBL24553896 | 0.72 | HTT (0.50) | LMNAPOLBGAAKMT2ASMN1; SMN2 | |
| SCHEMBL29227807 | 0.71 | S1PR3 (0.48) | LMNAS1PR3GAAKDM4EMEN1 | |
| SCHEMBL30195080 | 0.68 | LMNA (0.48) | LMNAPOLBGAASMN1; SMN2HTT | |
| SCHEMBL3724833 | 0.68 | HTT (0.49) | LMNAPOLBGAASMN1; SMN2HTT | |
| SCHEMBL23087297 | 0.66 | HTT (0.48) | LMNAPOLBGAASMN1; SMN2HTT | |
| SCHEMBL22256953 | 0.66 | SLCO1B1 (0.45) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3685143 | 0.65 | KAT2B (0.34) | LMNAPOLB | |
| SCHEMBL9542160 | 0.64 | MEN1 (0.71) | LMNAS1PR3GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703806-B | Phosphine ligand of pyrazole-amide framework, and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-115703806-A | Phosphine ligand with pyrazole-amide skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2023-02-17 | — | — | CN | disclosed |