Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30960385 | 0.82 | LMNA (0.38) | LMNAPOLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL12261124 | 0.81 | LMNA (0.58) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL1357879 | 0.74 | HTT (0.50) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL24553896 | 0.74 | HTT (0.50) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL30194977 | 0.74 | LMNA (0.52) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL30195080 | 0.73 | LMNA (0.48) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL3724833 | 0.73 | HTT (0.49) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL23087297 | 0.72 | HTT (0.48) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL4813243 | 0.70 | CYP1A2 (0.59) | LMNAPOLBHTTSMN1; SMN2GAA | |
| SCHEMBL30194933 | 0.70 | LMNA (0.33) | LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703806-B | Phosphine ligand of pyrazole-amide framework, and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-115703806-A | Phosphine ligand with pyrazole-amide skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2023-02-17 | — | — | CN | disclosed |