Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261124 | 0.77 | LMNA (0.58) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL1357879 | 0.75 | HTT (0.50) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL30194971 | 0.72 | CHRM4 (0.38) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL24553896 | 0.71 | HTT (0.50) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL29227809 | 0.70 | GPR52 (0.46) | HTTSMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL3724833 | 0.70 | HTT (0.49) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL23087747 | 0.69 | KMT2A (0.42) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL14811783 | 0.69 | PDE10A (0.41) | ALDH1A1GAA | |
| SCHEMBL23087297 | 0.68 | HTT (0.48) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL4813243 | 0.67 | CYP1A2 (0.59) | LMNAHTTSMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703806-B | Phosphine ligand of pyrazole-amide framework, and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-115703806-A | Phosphine ligand with pyrazole-amide skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2023-02-17 | — | — | CN | disclosed |