Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227813 | 0.81 | S1PR3 (0.39) | KMT2A | |
| SCHEMBL30194933 | 0.81 | LMNA (0.33) | PDE10AALDH1A1POLB | |
| SCHEMBL30195080 | 0.72 | LMNA (0.48) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28841006 | 0.64 | ADRA1A (0.38) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29790554 | 0.64 | ADRA1A (0.38) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5266975 | 0.62 | ALDH1A1 (0.43) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1315359 | 0.61 | ROCK2 (0.35) | PKMKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29391340 | 0.61 | ALDH1A1 (0.40) | KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL29227809 | 0.61 | GPR52 (0.46) | CHRM4CHRM3CHRM5CHRM1CHRM2 | |
| SCHEMBL2847317 | 0.61 | KDM4E (0.33) | PKMKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703806-B | Phosphine ligand of pyrazole-amide framework, and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-115703806-A | Phosphine ligand with pyrazole-amide skeleton and preparation method and application thereof | 香港理工大学深圳研究院 | 2023-02-17 | — | — | CN | disclosed |