Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695569 | 0.85 | MEN1 (0.50) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10695456 | 0.85 | KMT2A (0.53) | TBXAS1KMT2ASMN1; SMN2 | |
| SCHEMBL7362509 | 0.83 | NAPRT (0.72) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8664876 | 0.83 | HDAC1 (0.67) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL1538161 | 0.83 | NAPRT (0.57) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3253168 | 0.81 | NAPRT (0.74) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28975712 | 0.80 | NAPRT (0.62) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30612524 | 0.80 | TBXAS1 (0.90) | TBXAS1NAPRTHDAC3MAPK1ADRA1A | |
| SCHEMBL30195679 | 0.80 | NAPRT (0.62) | TBXAS1NAPRTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1583762 | 0.80 | TBXAS1 (0.90) | TBXAS1NAPRTHDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |