Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 7/20 | 0.42 |
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | CTSE | P14091 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 5/20 | 0.40 |
| ▸ | NPY4R | P50391 | 5/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.40 |
| ▸ | NPY1R | P25929 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30286103 | 0.91 | CAPN1 (0.43) | CAPN1STAT3CTSDCTSEBACE1 | |
| SCHEMBL30539771 | 0.91 | CTSD (0.42) | CAPN1STAT3CTSDBACE1NTSR2 | |
| Larazotide SCHEMBL23668121 | 0.89 | CAPN1 (0.43) | CAPN1STAT3CTSDCTSEBACE1 | |
| Larazotide SCHEMBL23668120 | 0.89 | CAPN1 (0.43) | CAPN1STAT3CTSDCTSEBACE1 | |
| Larazotide SCHEMBL28795844 | 0.89 | CAPN1 (0.43) | CAPN1STAT3CTSDCTSEBACE1 | |
| Larazotide SCHEMBL29366234 | 0.88 | CAPN1 (0.42) | CAPN1STAT3CTSDCTSEBACE1 | |
| SCHEMBL31461934 | 0.86 | CAPN1 (0.47) | CAPN1STAT3NTSR2NTSR1NPY2R | |
| SCHEMBL31461940 | 0.86 | CAPN1 (0.47) | CAPN1STAT3NTSR2NTSR1NPY2R | |
| SCHEMBL31462120 | 0.85 | NPY2R (0.46) | CAPN1NTSR2NTSR1NPY2RNPY4R | |
| SCHEMBL29692555 | 0.84 | NTSR2 (0.40) | CAPN1STAT3NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218706-A1 | LARAZOTIDE DERIVATIVES COMPRISING D-AMINO ACIDS | INNOVATE BIOPHARMACEUTICALS, INC. | 2023-07-13 | — | — | US | disclosed |
| CN-115916235-A | Larzoledrine derivatives comprising D-amino acids | 九米特生物制药有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-4135737-A1 | LARAZOTIDE DERIVATIVES COMPRISING D-AMINO ACIDS | 9 Meters Biopharma, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |