Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | CTSE | P14091 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 7/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Larazotide SCHEMBL28795844 | 0.96 | CAPN1 (0.43) | CAPN1KDM1ACTSDCTSEBACE1 | |
| Larazotide SCHEMBL23668121 | 0.96 | CAPN1 (0.43) | CAPN1KDM1ACTSDCTSEBACE1 | |
| Larazotide SCHEMBL23668120 | 0.96 | CAPN1 (0.43) | CAPN1KDM1ACTSDCTSEBACE1 | |
| Larazotide SCHEMBL29366234 | 0.95 | CAPN1 (0.42) | CAPN1KDM1ACTSDCTSEBACE1 | |
| SCHEMBL30197449 | 0.91 | CAPN1 (0.44) | CAPN1KDM1ACTSDCTSEBACE1 | |
| SCHEMBL29567142 | 0.90 | ELANE (0.42) | CAPN1STAT3NTSR1NTSR2 | |
| SCHEMBL30539771 | 0.89 | CTSD (0.42) | CAPN1CTSDBACE1STAT3NTSR1 | |
| SCHEMBL29567365 | 0.87 | NTSR1 (0.40) | CAPN1STAT3NTSR1NTSR2OPRD1 | |
| SCHEMBL29567235 | 0.87 | NTSR1 (0.40) | CAPN1STAT3NTSR1NTSR2OPRD1 | |
| SCHEMBL29567257 | 0.86 | XIAP (0.44) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218706-A1 | LARAZOTIDE DERIVATIVES COMPRISING D-AMINO ACIDS | INNOVATE BIOPHARMACEUTICALS, INC. | 2023-07-13 | — | — | US | disclosed |
| CN-115916235-A | Larzoledrine derivatives comprising D-amino acids | 九米特生物制药有限公司 | 2023-04-04 | — | — | CN | disclosed |