Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | PNMT | P11086 | 2/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199396 | 1.00 | DRD2 (0.57) | DRD2DRD3PNMTCD274HRH3 | |
| SCHEMBL29097839 | 1.00 | DRD2 (0.57) | DRD2DRD3PNMTCD274HRH3 | |
| SCHEMBL29097955 | 0.95 | DRD2 (0.57) | DRD2DRD3PNMTCD274HRH3 | |
| SCHEMBL30199147 | 0.95 | DRD2 (0.57) | DRD2DRD3PNMTCD274HRH3 | |
| SCHEMBL30199135 | 0.86 | PNMT (0.44) | DRD2DRD3PNMTCD274PRMT5 | |
| SCHEMBL29098094 | 0.86 | PNMT (0.44) | DRD2DRD3PNMTCD274PRMT5 | |
| SCHEMBL29098052 | 0.82 | DRD2 (0.60) | DRD2DRD3PNMTHRH3ADRA2A | |
| SCHEMBL30199515 | 0.82 | CD274 (0.57) | PNMTCD274HRH3ADRA2AADRA2B | |
| SCHEMBL30199078 | 0.82 | DRD2 (0.60) | DRD2DRD3PNMTHRH3ADRA2A | |
| SCHEMBL29097827 | 0.82 | CD274 (0.57) | PNMTCD274HRH3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |