Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199135 | 1.00 | PNMT (0.44) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL30199623 | 0.91 | DRD2 (0.40) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL29097991 | 0.91 | DRD2 (0.40) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL29097839 | 0.86 | DRD2 (0.57) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL30199144 | 0.86 | DRD2 (0.57) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL29097955 | 0.86 | DRD2 (0.57) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL30199396 | 0.86 | DRD2 (0.57) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL30199147 | 0.86 | DRD2 (0.57) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL30199560 | 0.77 | HDAC1 (0.48) | PNMTDRD2DRD3PRMT5EGFR | |
| SCHEMBL29098107 | 0.77 | HDAC1 (0.48) | PNMTDRD2DRD3PRMT5EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |