Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228082 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL15541404 | 0.89 | PIN1 (0.52) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL6320 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL30585356 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL9200645 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL1662886 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL2986961 | 0.83 | MAPT (0.48) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL1981547 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL2987569 | 0.83 | TLR4 (0.53) | MAPK1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL30639026 | 0.83 | MAPT (0.67) | ALDH1A1MAPK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121029-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | Amathus Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |