Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585356 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL30199709 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL228082 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL1662886 | 0.82 | ALDH1A1 (0.65) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL12992246 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL10340370 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL8211036 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL9157246 | 0.81 | MAPT (0.62) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL15541009 | 0.80 | MAPT (0.48) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL3501410 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791392-A | Method for synthesizing melarsoprol and intermediate compound | 华中科技大学 | 2024-10-18 | — | — | CN | claimed |
| CN-118702588-A | Preparation method of ilast and intermediate thereof | 重庆华邦胜凯制药有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-117143097-A | Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2023-12-01 | — | — | CN | claimed |
| CN-119431405-B | Indolo [3,2-b ] carbazole dimer derivative, and preparation method and application thereof | 沈阳药科大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20250368667-A1 | USP1 INHIBITOR | SHANGHAI QILU PHARMACEUTICAL RES AND DEVELOPMENT CENTRE LTD (CN) | 2025-12-04 | — | — | US | disclosed |
| EP-4631573-A2 | TEAD INHIBITORS | Orion Corporation (FI) | 2025-10-15 | — | — | EP | disclosed |
| EP-4323338-B1 | TEAD INHIBITORS | ORION CORP (FI) | 2025-10-08 | — | — | EP | disclosed |
| US-20250270215-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-08-28 | — | — | US | disclosed |
| EP-4582427-A1 | USP1 INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2025-07-09 | — | — | EP | disclosed |
| US-20250195668-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | THE BROAD INSTITUTE, INC. | 2025-06-19 | — | — | US | disclosed |
| US-20250171447-A1 | ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-05-29 | — | — | US | disclosed |
| WO-1998038991-A1 | POLYCYCLIC ETHYL ALKYLAMIDE MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |
| WO-1998012190-A2 | PHENOXATHIIN DERIVATIVES AS INHIBITORS OF MONOAMINE OXIDASE | KRENITSKY PHARMACEUTICAL, INC. (US) | 1998-03-26 | — | — | WO | disclosed |
| US-5677328-A | SLEEP DISORDERS; PSYCHOLOGICAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-10-14 | — | — | US | disclosed |
| EP-0771791-A1 | Ethylamino carbazole melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5576324-A | Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same | KOWA CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| US-5461046-A | Analgesics | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0638571-A1 | QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5304644-A | 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain | G. D. SEARLE & CO. (US) | 1994-04-19 | — | — | US | disclosed |
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171447-A1 | ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE THEREOF | ADORA2A, ADORA2B, ADORA1 | ALDH1A1 483/4885MAPK1 3063/4885MAPT 4454/4885 |
| US-20250195668-A1 | BIFUNCTIONAL MOLECULES FOR SELECTIVE MODIFICATION OF TARGET SUBSTRATES | COASY, JMJD7, PTMS | ALDH1A1 1238/4885MAPK1 3733/4885MAPT 3572/4885 |
| US-20250368667-A1 | USP1 INHIBITOR | USP1, USP2, USP28 | ALDH1A1 644/4885MAPK1 1205/4885MAPT 2468/4885 |
| US-20250270215-A1 | IMIDAZOLE DERIVATIVES AS ALK5 INHIBITORS | ALK, TGFBR1, TGFBR2 | ALDH1A1 828/4885MAPK1 277/4885MAPT 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.