Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30198973 | 0.85 | NR1H2 (0.52) | NPC1RAB9AHDAC8 | |
| SCHEMBL29098008 | 0.85 | NR1H2 (0.52) | NPC1RAB9AHDAC8 | |
| SCHEMBL29097884 | 0.81 | TAS1R3 (0.46) | KMT2AMEN1GAATMPRSS2NPC1 | |
| SCHEMBL30474301 | 0.81 | ERCC1 (0.45) | ERCC1ERCC4KMT2AMEN1CXCR3 | |
| SCHEMBL13623452 | 0.77 | ESR1 (0.50) | ERCC1ERCC4KMT2AMEN1GAA | |
| SCHEMBL29390456 | 0.77 | ESR1 (0.50) | ERCC1ERCC4KMT2AMEN1GAA | |
| SCHEMBL29098005 | 0.73 | PNMT (0.55) | KMT2AMEN1HTR2CHTR2B | |
| SCHEMBL30200120 | 0.73 | PNMT (0.55) | KMT2AMEN1HTR2CHTR2B | |
| SCHEMBL17317767 | 0.72 | ENPP2 (0.41) | ERCC1ERCC4CXCR3HDAC1HDAC6 | |
| SCHEMBL29097943 | 0.72 | MRGPRX4 (0.52) | KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |