Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.68 |
| ▸ | RELA | Q04206 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 12/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945400 | 0.83 | RAB9A (0.73) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL20614446 | 0.82 | ROCK2 (0.48) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL1131467 | 0.82 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL28310352 | 0.78 | RAB9A (0.79) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6037573 | 0.77 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL8071379 | 0.77 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6037569 | 0.77 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL7570608 | 0.77 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4534378 | 0.76 | RAB9A (0.71) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL12258528 | 0.75 | SMN1; SMN2 (0.80) | RAB9ASMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647311-B1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-11-01 | — | — | EP | disclosed |
| US-20230030115-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230030115-A1 | RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF | ROCK1, ROCK2, RHOA | RAB9A 245/4885SMN1; SMN2 2820/4885NFKB1 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.