Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | APLNR | P35414 | 3/20 | 0.48 |
| ▸ | BMP1 | P13497 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003011 | 0.78 | BMP1 (0.73) | ALDH1A1BMP1KMT2A | |
| SCHEMBL3675681 | 0.78 | ALOX5 (0.57) | KMT2A | |
| SCHEMBL27266465 | 0.77 | APLNR (0.58) | ALDH1A1APLNRBMP1TAS2R14PTGES | |
| SCHEMBL27266410 | 0.77 | APLNR (0.58) | APLNRBMP1TAS2R14PTGESTAS2R8 | |
| SCHEMBL7999711 | 0.76 | ALOX5 (0.59) | KMT2A | |
| SCHEMBL16235820 | 0.76 | APLNR (0.65) | APLNRBMP1TAS2R14CNR2PTGES | |
| SCHEMBL3586758 | 0.75 | APLNR (0.59) | ALDH1A1APLNRBMP1TAS2R14PTGES | |
| SCHEMBL19285058 | 0.75 | APLNR (0.59) | APLNRBMP1TAS2R14PTGESTAS2R8 | |
| SCHEMBL1239542 | 0.75 | ALOX5 (0.65) | ALDH1A1KMT2A | |
| SCHEMBL26646257 | 0.75 | APLNR (0.55) | ALDH1A1APLNRBMP1TAS2R14PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401729-A1 | BCL-XL DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023044046-A1 | BCL-XL DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |