Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579104 | 0.77 | MTNR1A (0.57) | MTNR1AMTNR1BSLC6A4PPARGPPARA | |
| SCHEMBL3579103 | 0.77 | MTNR1A (0.57) | MTNR1AMTNR1BSLC6A4PPARGPPARA | |
| Xylamidine SCHEMBL31307218 | 0.75 | MTNR1A (0.58) | MTNR1AMTNR1BMEN1KMT2AALDH1A1 | |
| SCHEMBL31231248 | 0.71 | MTNR1A (0.48) | MTNR1AMTNR1BKMT2AHPGDALDH1A1 | |
| Xylamidine SCHEMBL30201100 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL11230310 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A4PPARGPPARA | |
| SCHEMBL30201012 | 0.70 | MTNR1B (0.55) | MTNR1AMTNR1BMEN1KMT2ALMNA | |
| SCHEMBL30201980 | 0.70 | MAPT (0.36) | MTNR1AMTNR1BSLC6A4MEN1KMT2A | |
| SCHEMBL10829122 | 0.67 | MTNR1B (0.46) | MTNR1AMTNR1BMEN1KMT2AHPGD | |
| Xylamidine SCHEMBL123846 | 0.67 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028086-A1 | COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |