Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416433 | 1.00 | POLB (0.50) | POLBALOX5OR51E2MAPTNPSR1 | |
| SCHEMBL4643463 | 0.86 | CYP4F2 (0.52) | POLBMAPTNPSR1APPALDH1A1 | |
| SCHEMBL286994 | 0.85 | ALDH1A1 (0.59) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL31170840 | 0.85 | ALDH1A1 (0.59) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL14565801 | 0.84 | LMNA (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL1644381 | 0.84 | ALDH1A1 (0.48) | POLBMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL4850663 | 0.84 | LMNA (0.47) | POLBMAPTALDH1A1HPGDTSHR | |
| SCHEMBL3949693 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL9375548 | 0.84 | POLB (0.50) | POLBMAPTNPSR1ALDH1A1MAPK1 | |
| SCHEMBL11009236 | 0.83 | IAPP (0.53) | POLBALOX5OR51E2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912683-B | Cytotoxin molecule, conjugate, preparation method and application thereof | 杭州多禧生物科技有限公司 | 2023-01-06 | — | — | CN | disclosed |