Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775542 | 1.00 | ALDH1A1 (0.52) | ALDH1A1FFAR4MRGPRX4RXRARXRB | |
| SCHEMBL29718989 | 0.86 | RXRA (0.50) | ALDH1A1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL838070 | 0.86 | RXRA (0.50) | ALDH1A1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL14263413 | 0.85 | ALDH1A1 (0.45) | ALDH1A1FFAR4MRGPRX4MEN1KMT2A | |
| SCHEMBL30591389 | 0.85 | ALDH1A1 (0.48) | ALDH1A1FFAR4MRGPRX4MEN1KMT2A | |
| SCHEMBL31750436 | 0.83 | FFAR1 (0.54) | ALDH1A1FFAR4MEN1KMT2AKCNJ5 | |
| SCHEMBL31204321 | 0.83 | ALDH1A1 (0.44) | ALDH1A1FFAR4MRGPRX4MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5769358 | 0.82 | FFAR1 (0.47) | ALDH1A1FFAR4MRGPRX4RXRARXRB | |
| Hydrochloric Acid SCHEMBL34474962 | 0.82 | FFAR1 (0.53) | ALDH1A1FFAR4MEN1KMT2AKCNJ5 | |
| Trifluoroacetic Acid SCHEMBL34475312 | 0.81 | FFAR1 (0.52) | ALDH1A1FFAR4MEN1KMT2AKCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028056-A1 | 3-AMINO PIPERIDYL SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |