Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921145 | 0.78 | CCR1 (0.58) | L3MBTL1GRM5NTRK1PIM1KDM4E | |
| SCHEMBL3149107 | 0.76 | L3MBTL1 (0.42) | L3MBTL1GRM5NTRK1PIM1KDM4E | |
| SCHEMBL14752348 | 0.76 | KDM5C (0.54) | KDM4EMAPTALDH1A1 | |
| SCHEMBL29972725 | 0.75 | L3MBTL1 (0.43) | L3MBTL1GRM5NTRK1PIM1KDM4E | |
| SCHEMBL6669276 | 0.75 | L3MBTL1 (0.43) | L3MBTL1GRM5NTRK1PIM1KDM4E | |
| SCHEMBL24921750 | 0.74 | L3MBTL1 (0.41) | L3MBTL1GRM5NTRK1PIM1KDM4E | |
| SCHEMBL2655803 | 0.74 | HTT (0.65) | L3MBTL1GRM5KDM4EPKMTP53 | |
| SCHEMBL31478766 | 0.74 | HTT (0.65) | L3MBTL1GRM5KDM4EPKMTP53 | |
| SCHEMBL17055753 | 0.73 | ACHE (0.45) | L3MBTL1GRM5PKMTP53MEN1 | |
| SCHEMBL2386959 | 0.71 | L3MBTL1 (0.77) | L3MBTL1GRM5KDM4ETP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387609-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023532-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |