SCHEMBL9779306

SCHEMBL9779306

O=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.56
MAPK1 P28482 1/20 0.55
LMNA P02545 2/20 0.53
HTT P42858 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
NR4A1 P22736 1/20 0.52
USP2 O75604 1/20 0.52
GAA P10253 1/20 0.52
KEAP1 Q14145 1/20 0.52
NFE2L2 Q16236 1/20 0.52
MAPT P10636 3/20 0.51
RAB9A P51151 3/20 0.51
CNR1 P21554 1/20 0.51
CNR2 P34972 1/20 0.51
F2 P00734 1/20 0.49
F10 P00742 1/20 0.49
PLG P00747 1/20 0.49
PLAU P00749 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23464098 0.89 PLAU (0.51) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL3029820 0.89 KCNMA1 (0.53) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL460727 0.89 MEN1 (0.68) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL3812381 0.89 MEN1 (0.68) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL30204017 0.89 MEN1 (0.68) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL27612735 0.87 CA1 (0.54) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL9002496 0.85 MEN1 (0.56) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL9779330 0.84 CA1 (0.62) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL31556214 0.82 CES2 (0.61) SRD5A2MAPK1LMNAHTTKDM4E
SCHEMBL9496067 0.82 SRD5A2 (0.79) SRD5A2MAPK1HTTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066695-A Plastics; heat resistance, dispersibility CIBA-GEIGY CORPORATION (US) 1991-11-19 US disclosed
EP-0168343-B1 METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING HIGH-MOLECULAR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1991-05-02 EP disclosed
EP-0169167-B1 PROCESS FOR DYEING HIGH-MOLECULAR ORGANIC MATERIALS, AND METAL COMPLEXES CIBA-GEIGY AG (CH) 1990-05-02 EP disclosed
US-4775747-A PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US disclosed
US-4639477-A AZO DYES CIBA-GEIGY CORPORATION (US) 1987-01-27 US disclosed
EP-0168343-A2 Metal complexes, process for their preparation and their use in dyeing high-molecular organic materials CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed