Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204361 | 0.85 | ALKBH2 (0.51) | POLBIRAK4NR3C1FFAR4KDM4E | |
| SCHEMBL30040685 | 0.84 | IRAK4 (0.48) | POLBIRAK4NR3C1FFAR4NPC1 | |
| SCHEMBL3973189 | 0.79 | POLB (0.55) | ALOX15HTTCYP11B1CYP11B2POLB | |
| SCHEMBL31556376 | 0.79 | POLB (0.55) | ALOX15HTTCYP11B1CYP11B2POLB | |
| SCHEMBL23535745 | 0.79 | CYP11B1 (0.60) | ALOX15HTTCYP11B1CYP11B2NR3C1 | |
| SCHEMBL20373135 | 0.77 | CYP11B1 (0.47) | ALOX15HTTCYP11B1CYP11B2GAA | |
| SCHEMBL24976359 | 0.77 | CYP11B1 (0.47) | ALOX15HTTCYP11B1CYP11B2TSHR | |
| SCHEMBL348090 | 0.76 | CYP11B1 (0.57) | CYP11B1CYP11B2NR3C1RAB9AKDM4E | |
| SCHEMBL1363389 | 0.75 | CYP11B1 (0.69) | CYP11B1CYP11B2NR3C1 | |
| SCHEMBL31632962 | 0.75 | CYP11B2 (0.65) | CYP11B1CYP11B2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337662-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | Bridge Medicines (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |