Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025404 | 0.78 | KDM4C (0.40) | KDM4C | |
| SCHEMBL3665960 | 0.78 | OPRD1 (0.37) | KDM4C | |
| SCHEMBL1415498 | 0.72 | HTR6 (0.51) | HTR6 | |
| SCHEMBL1415344 | 0.72 | HTR6 (0.56) | HTR6ESR1ESR2 | |
| SCHEMBL17258086 | 0.69 | BRD4 (0.43) | HTR6 | |
| Hydrochloric Acid SCHEMBL9523688 | 0.68 | BRD4 (0.43) | HTR6 | |
| SCHEMBL6670411 | 0.68 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL7796027 | 0.68 | SIGMAR1 (0.46) | — | |
| SCHEMBL13213531 | 0.68 | HTR6 (0.41) | HTR6ESR1ESR2 | |
| SCHEMBL10752692 | 0.67 | BRD4 (0.42) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | NRDC, MRPL21, NISCH | HTR6 3665/4885KDM4C 3322/4885ESR1 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.