Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYD88 | Q99836 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205261 | 0.91 | MYD88 (0.48) | MYD88ALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL30205266 | 0.83 | CA1 (0.45) | MYD88TDP1MEN1KMT2APOLB | |
| SCHEMBL28954767 | 0.74 | MYD88 (1.00) | MYD88ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30585268 | 0.73 | MYD88 (0.55) | MYD88ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL28954834 | 0.71 | MYD88 (0.64) | MYD88ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL29078406 | 0.70 | MYD88 (0.68) | MYD88ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30585272 | 0.69 | ALDH1A1 (0.55) | MYD88ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL29078389 | 0.68 | MYD88 (0.60) | MYD88ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL15800712 | 0.67 | ALDH1A1 (0.78) | ALDH1A1KDM4ETDP1MEN1GAA | |
| SCHEMBL6858096 | 0.65 | MEN1 (0.65) | ALDH1A1KDM4ETDP1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710251-A | Myeloid differentiation factor 88 inhibitor and preparation method and application thereof | 杭州医学院 | 2023-02-24 | — | — | CN | disclosed |