SCHEMBL30206595

SCHEMBL30206595

COC(=O)c1cc(CCl)nn1-c1ncccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 5/20 0.38
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
RBP4 P02753 1/20 0.38
ALDH1A1 P00352 2/20 0.37
DHODH Q02127 1/20 0.37
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL421559 1.00 MALT1 (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL955031 0.96 MALT1 (0.36) MALT1SLC16A3SLC16A1RBP4ALDH1A1
Hydrochloric Acid SCHEMBL959170 0.92 SLC16A3 (0.36) MALT1SLC16A3SLC16A1RBP4DHODH
SCHEMBL340847 0.91 MALT1 (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL2623669 0.91 MALT1 (0.39) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL25008752 0.89 SLC16A3 (0.41) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL341689 0.89 DHODH (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL16014672 0.89 MALT1 (0.37) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL28802119 0.88 ALDH1A1 (0.38) MALT1SLC16A3SLC16A1RBP4ALDH1A1
SCHEMBL341122 0.86 ALDH1A1 (0.37) MALT1SLC16A3SLC16A1RBP4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376616-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-05 EP disclosed
WO-2023006634-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-02 WO disclosed