SCHEMBL341689

SCHEMBL341689

COC(=O)c1cc(CBr)nn1-c1ncccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.38
MALT1 Q9UDY8 6/20 0.37
SLC16A3 O15427 1/20 0.37
SLC16A1 P53985 1/20 0.37
RBP4 P02753 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28802119 0.92 ALDH1A1 (0.38) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL2623669 0.89 MALT1 (0.39) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL30206595 0.89 MALT1 (0.38) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL340847 0.89 MALT1 (0.38) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL421559 0.89 MALT1 (0.38) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL25082886 0.89 ALDH1A1 (0.45) SLC16A3SLC16A1ALDH1A1POLBTDP1
SCHEMBL16014672 0.88 MALT1 (0.37) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL25008752 0.88 SLC16A3 (0.41) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL341122 0.85 ALDH1A1 (0.37) DHODHMALT1SLC16A3SLC16A1RBP4
SCHEMBL955031 0.85 MALT1 (0.36) DHODHMALT1SLC16A3SLC16A1RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES DDT, QDPR, ANTXR2 DHODH 197/4885MALT1 4605/4885SLC16A3 4086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.