Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 1.00 |
| ▸ | MTNR1A | P48039 | 1/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 1/20 | 1.00 |
| ▸ | GPR68 | Q15743 | 6/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | TPH1 | P17752 | 5/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ogerin SCHEMBL29407423 | 0.73 | GPR68 (1.00) | HTR2BMTNR1AMTNR1BGPR68ADORA2A | |
| SCHEMBL3301514 | 0.64 | NPSR1 (0.74) | HTR2BGPR68ADORA2ATPH1HTR1A | |
| SCHEMBL6727019 | 0.64 | NPSR1 (0.74) | HTR2BGPR68ADORA2AHTR1ANPSR1 | |
| Hydrochloric Acid SCHEMBL9247173 | 0.63 | NPSR1 (0.72) | HTR2BGPR68ADORA2AHTR1ANPSR1 | |
| SCHEMBL18177442 | 0.63 | SMN1; SMN2 (0.53) | HTR2BMTNR1AMTNR1BTPH1 | |
| SCHEMBL510065 | 0.62 | LTA4H (1.00) | LTA4H | |
| SCHEMBL1744936 | 0.62 | LTA4H (1.00) | LTA4H | |
| SCHEMBL29223873 | 0.62 | CA1 (0.60) | GPR68NPSR1APP | |
| SCHEMBL31262715 | 0.61 | HTR2B (0.43) | HTR2BMTNR1AMTNR1BADORA2A | |
| SCHEMBL30748835 | 0.61 | MAPT (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285878-A1 | METHODS FOR DETECTING, TREATING, AND PREVENTING GPR68-MEDIATED OCULAR DISEASES, DISORDERS, AND CONDITIONS | AVIATION-OPHTHALMOLOGY (SE) | 2023-01-19 | — | — | WO | claimed |