Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189562 | 0.73 | L3MBTL1 (0.58) | DCPSKMT2AL3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL29109414 | 0.71 | DCPS (0.57) | DCPSNPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL30208425 | 0.70 | DCPS (0.45) | DCPSNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL29631138 | 0.69 | DCPS (0.44) | DCPSNPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL28229720 | 0.68 | KDM4E (0.55) | DCPSCYP1A2CYP1A1CYP1B1APP | |
| SCHEMBL16589007 | 0.68 | DCPS (0.57) | DCPSNPC1RAB9AKMT2ATAAR1 | |
| SCHEMBL29563950 | 0.67 | LATS1 (0.33) | — | |
| SCHEMBL31061156 | 0.66 | CLK1 (0.66) | CLK1DCPSNPC1RAB9AKMT2A | |
| SCHEMBL12733670 | 0.66 | CLK1 (0.66) | CLK1DCPSNPC1RAB9AKMT2A | |
| SCHEMBL1675370 | 0.66 | CLK1 (0.66) | CLK1DCPSNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641886-B | Bicyclic BET bromodomain inhibitors and uses thereof | 康威基内有限公司 | 2022-11-18 | — | — | CN | disclosed |