Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 11/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 9/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631138 | 0.82 | DCPS (0.44) | — | |
| SCHEMBL29564263 | 0.74 | PRMT5 (0.41) | — | |
| SCHEMBL5768942 | 0.72 | LATS1 (0.38) | LATS1LATS2ACHEKDM4C | |
| SCHEMBL29564197 | 0.70 | ADORA2A (0.42) | — | |
| SCHEMBL250853 | 0.70 | ACHE (0.42) | LATS1LATS2ACHERPS6KA5KDM4C | |
| SCHEMBL20952805 | 0.68 | HRH3 (0.36) | — | |
| SCHEMBL30208323 | 0.67 | CLK1 (0.45) | — | |
| SCHEMBL26157957 | 0.66 | DCPS (0.55) | ACHEDYRK1A | |
| SCHEMBL13051982 | 0.65 | APLNR (0.39) | — | |
| SCHEMBL5768328 | 0.63 | HASPIN (0.46) | LATS1LATS2ACHEKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976609-A1 | PYRIDOPYRIMIDINES DERIVATIVES AS P2X3 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2022-04-06 | — | — | EP | claimed |