Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | HINT1 | P49773 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208557 | 0.86 | POLA1 (0.52) | TAS1R3TAS1R1 | |
| SCHEMBL30208535 | 0.84 | HPGD (0.54) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL30208450 | 0.83 | HPGD (0.54) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL30208628 | 0.83 | LMNA (0.54) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL382557 | 0.79 | TAS1R3 (0.77) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL413506 | 0.79 | TAS1R3 (0.77) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL382556 | 0.79 | TAS1R3 (0.77) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL30208547 | 0.79 | HPGD (0.60) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL30208614 | 0.78 | HPGD (0.59) | HPGDTAS1R3TAS1R1ADORA2AADORA3 | |
| SCHEMBL26246701 | 0.77 | HPGD (0.66) | HPGDTAS1R3TAS1R1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | claimed |
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | disclosed |