Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208544 | 0.85 | SLC29A1 (0.49) | SLC29A1ADORA3 | |
| SCHEMBL31286196 | 0.83 | ADORA3 (0.67) | LMNATSHRHTTRXFP1ADORA2A | |
| SCHEMBL30208502 | 0.83 | SLC29A1 (0.56) | LMNATSHRHTTRXFP1ADORA2A | |
| SCHEMBL30208503 | 0.83 | SLC29A1 (0.56) | LMNATSHRHTTRXFP1ADORA2A | |
| SCHEMBL30208559 | 0.83 | HPGD (0.54) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL30208525 | 0.82 | SLC29A1 (0.57) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL28477260 | 0.81 | ADORA2A (0.67) | LMNATSHRHTTRXFP1ADORA2A | |
| SCHEMBL28872479 | 0.81 | ADORA2A (0.64) | LMNATSHRHTTRXFP1ADORA2A | |
| SCHEMBL28758971 | 0.78 | ADORA2A (0.65) | LMNATSHRHTTRXFP1ADORA2A | |
| SCHEMBL24920112 | 0.77 | ADORA2A (0.67) | LMNATSHRHTTRXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | claimed |
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | disclosed |