Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 16/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484311 | 0.97 | GLP1R (0.56) | GLP1RGCGRIL23R | |
| SCHEMBL30183034 | 0.95 | GLP1R (0.55) | GLP1RCXCR4IL23R | |
| SCHEMBL30208639 | 0.95 | GLP1R (0.60) | GLP1RCXCR4GCGRIL23R | |
| SCHEMBL30338573 | 0.94 | GLP1R (0.54) | GLP1RCXCR4GCGRIL23R | |
| SCHEMBL30388309 | 0.94 | IL23R (0.53) | GLP1RCXCR4IL23R | |
| SCHEMBL29484313 | 0.92 | NPBWR1 (0.55) | GLP1RCXCR4GCGRIL23R | |
| SCHEMBL29484310 | 0.92 | CTSL (0.53) | GLP1RCXCR4IL23R | |
| SCHEMBL30064553 | 0.92 | GLP1R (0.58) | GLP1RIL23R | |
| SCHEMBL29484320 | 0.91 | IL23R (0.53) | GLP1RCXCR4GCGRIL23R | |
| SCHEMBL30216222 | 0.91 | GLP1R (0.52) | GLP1RCXCR4IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118217402-A | Combination therapy for C3 inhibition | 阿佩利斯制药有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117503905-A | dosing regimen | 阿佩利斯制药有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-110882376-B | Cell-reactive, long-acting or targeted compstatin analogs and related compositions and methods | 阿佩利斯制药公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116059313-A | Dosing regimen and related compositions and methods | 阿佩利斯制药有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-110831544-B | Long-acting compstatin analogs, dosing regimens for compositions thereof, and medical uses thereof | 阿佩利斯制药有限公司 | 2022-11-18 | — | — | CN | disclosed |