Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28427382 | 0.83 | RECQL (0.68) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL29012568 | 0.82 | KMT2A (0.73) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL2422002 | 0.82 | RECQL (1.00) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL30209485 | 0.81 | HSD11B1 (0.80) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL29609963 | 0.80 | RECQL (0.97) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL29012562 | 0.80 | HSD11B1 (0.83) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL12237263 | 0.80 | KMT2A (0.77) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL28554569 | 0.78 | HSD11B1 (0.69) | RECQLHSD11B1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10872654 | 0.78 | RECQL (0.91) | RECQLHSD11B1ALDH1A1MAPTKMT2A | |
| SCHEMBL31208425 | 0.77 | HSD11B1 (0.68) | RECQLHSD11B1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978216-B | Preparation method of beta-carbonyl sulfone compound | 西南医科大学 | 2023-02-03 | — | — | CN | disclosed |