Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 5/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.46 |
| ▸ | KDM4B | O94953 | 2/20 | 0.45 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607268 | 1.00 | CYP1A2 (0.47) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL5147899 | 0.85 | TSHR (0.51) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL509023 | 0.85 | CYP1A2 (0.47) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL7668183 | 0.85 | CYP1A2 (0.47) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL5566822 | 0.83 | CYP1A2 (0.46) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL15991431 | 0.83 | CYP1A2 (0.46) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| 2-Ethylisonicotinamide SCHEMBL2606610 | 0.83 | CYP1A2 (0.69) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL2305108 | 0.82 | KDM4C (0.57) | KDM4EKDM5CKDM5BKDM4CKDM5A | |
| SCHEMBL16115747 | 0.82 | KDM4E (0.49) | CYP1A2POLBKDM4ELMNACYP3A4 | |
| SCHEMBL24690842 | 0.81 | PKM (0.46) | CYP1A2POLBKDM4ELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695162-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-02-02 | — | — | US | disclosed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029416-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | CYP1A2 4100/4885POLB 4540/4885KDM4E 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.