Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796408 | 0.85 | SMN1; SMN2 (0.46) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL17454393 | 0.84 | ALDH1A1 (0.38) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL4791335 | 0.83 | KMT2A (0.38) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL17076692 | 0.81 | ALDH1A1 (0.38) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL17438035 | 0.81 | KMT2A (0.52) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL19902346 | 0.81 | ALDH1A1 (0.40) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL13254732 | 0.81 | CYP1A2 (0.41) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL17452573 | 0.80 | NPC1 (0.36) | CYP1A2CYP2D6TDP1KDM4EALOX15 | |
| SCHEMBL2661462 | 0.80 | KDM4C (0.41) | CYP1A2CYP2D6TDP1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL16737214 | 0.78 | L3MBTL1 (0.35) | CYP1A2CYP2D6TDP1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867348-A | Imidazopyrimidines as IL-17 modulators | 詹森药业有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |