SCHEMBL3021082

SCHEMBL3021082

COc1c(O)cccc1C=N

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.67
CA2 P00918 3/20 0.67
MAPT P10636 4/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
THRB P10828 1/20 0.43
BACE1 P56817 1/20 0.43
APP P05067 1/20 0.43
KDM4E B2RXH2 3/20 0.42
TP53 P04637 2/20 0.42
MAPK1 P28482 2/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
HSD17B10 Q99714 1/20 0.42
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16952390 0.82 CA1 (0.69) CA1CA2MAPTALDH1A1MEN1
SCHEMBL470709 0.80 CA1 (1.00) CA1CA2MAPTALDH1A1MEN1
SCHEMBL60621 0.80 CA1 (0.67) CA1CA2MAPTALDH1A1MEN1
SCHEMBL16989324 0.78 CA1 (0.65) CA1CA2MAPTALDH1A1MEN1
SCHEMBL16989326 0.78 CA1 (0.65) CA1CA2MAPTALDH1A1MEN1
2-Methoxyresorcinol SCHEMBL69297 0.78 CA2 (0.61) CA1CA2MAPTALDH1A1MEN1
SCHEMBL28576325 0.77 CA1 (0.62) CA1CA2MAPTALDH1A1MEN1
SCHEMBL2315019 0.76 CA1 (0.61) CA1CA2MAPTALDH1A1MEN1
SCHEMBL30372446 0.76 CA1 (0.61) CA1CA2MAPTALDH1A1MEN1
2-Methoxyresorcinol SCHEMBL10818280 0.75 CA2 (0.59) CA1CA2MAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956624-B2 Compositions and methods for treating skin with extract from Trametes ELC MANAGEMENT, LLC (US) 2015-02-17 US disclosed
US-20100203077-A1 Compositions And Methods For Treating Skin With Extract From Trametes ELC MANAGEMENT LLC 2010-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100203077-A1 Compositions And Methods For Treating Skin With Extract From Trametes TYR, CUTA, BRAF CA1 4883/4885CA2 4783/4885MAPT 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.