Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085735 | 1.00 | NOS3 (0.43) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL29124230 | 0.92 | NR4A2 (0.38) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL18824880 | 0.85 | NOS3 (0.39) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL19416821 | 0.81 | ALDH1A1 (0.37) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL16771464 | 0.81 | NR4A2 (0.38) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL31281606 | 0.79 | NR4A2 (0.37) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL28026927 | 0.79 | NOS3 (0.38) | NOS3NOS1NOS2NR4A2KMT2A | |
| SCHEMBL18989970 | 0.78 | NAPRT (0.42) | KMT2AMAPTBLMALDH1A1CYP3A4 | |
| SCHEMBL24611378 | 0.78 | PSMD14 (0.46) | NOS3NOS1NOS2HSP90AA1LMNA | |
| SCHEMBL827728 | 0.78 | NOS3 (0.50) | NOS3NOS1NOS2HSP90AA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |