SCHEMBL30211337

SCHEMBL30211337

O=C(Nc1ccccc1Oc1ccc2ccccc2c1)c1cc(Cl)ccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 3/20 0.54
KDR P35968 1/20 0.54
PARG Q86W56 7/20 0.53
PYGL P06737 2/20 0.53
PYGM P11217 2/20 0.53
TMPRSS4 Q9NRS4 2/20 0.52
KDM4E B2RXH2 2/20 0.51
LMNA P02545 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
HIF1A Q16665 1/20 0.51
NPC1 O15118 1/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 1/20 0.51
NPY1R P25929 1/20 0.51
HTT P42858 1/20 0.51
NPY2R P49146 1/20 0.51
RAB9A P51151 1/20 0.51
TAS1R3 Q7RTX0 1/20 0.50
TAS1R1 Q7RTX1 1/20 0.50
TAS1R2 Q8TE23 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2167466 1.00 KCNMA1 (0.54) KCNMA1KDRPARGPYGLPYGM
SCHEMBL7762895 0.87 MEN1 (0.58) PARGPYGLKDM4ELMNANPSR1
SCHEMBL330132 0.85 TMPRSS4 (0.63) KDRPARGPYGLPYGMTMPRSS4
SCHEMBL2167468 0.84 KDR (0.57) KCNMA1KDRPARGTMPRSS4KDM4E
SCHEMBL2167354 0.83 KCNMA1 (0.59) KCNMA1KDRTMPRSS4KDM4ELMNA
SCHEMBL30887952 0.83 KCNMA1 (0.59) KCNMA1KDRTMPRSS4KDM4ELMNA
SCHEMBL13928800 0.80 KCNMA1 (0.72) KCNMA1TMPRSS4KDM4ENPSR1HIF1A
SCHEMBL4366384 0.78 TMPRSS4 (0.69) KDRPARGTMPRSS4P2RX1
SCHEMBL29024718 0.77 NPC1 (0.72) KCNMA1TMPRSS4KDM4ENPC1MAPT
SCHEMBL30503652 0.77 NPC1 (0.72) KCNMA1TMPRSS4KDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 CN disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed