Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PNLIP | P16233 | 4/20 | 0.52 |
| ▸ | PARG | Q86W56 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211337 | 0.87 | KCNMA1 (0.54) | NPC1RAB9AMAPTLMNAHTT | |
| SCHEMBL2167466 | 0.87 | KCNMA1 (0.54) | NPC1RAB9AMAPTLMNAHTT | |
| SCHEMBL27696845 | 0.82 | TDP1 (0.60) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7762899 | 0.80 | LMNA (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL12368186 | 0.78 | TDP1 (0.63) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6408304 | 0.77 | MEN1 (0.69) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL12368159 | 0.76 | KMT2A (0.77) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6407924 | 0.76 | NPC1 (0.56) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7123098 | 0.76 | PYGL (0.83) | MEN1KMT2ARAB9ALMNAPYGL | |
| SCHEMBL7129478 | 0.75 | PYGL (0.72) | NPC1RAB9APYGLTDP1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070189-A1 | METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS | UNILEVER PLC (GB) | 2001-09-27 | — | — | WO | disclosed |