SCHEMBL30211651

SCHEMBL30211651

NC(=O)CC[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CS)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 9/20 0.52
▸ OPRM1 P35372 4/20 0.51
▸ OPRD1 P41143 4/20 0.51
▸ CAPN1 P07384 2/20 0.43
▸ GRB2 P62993 1/20 0.43
▸ NMUR2 Q9GZQ4 3/20 0.42
▸ NMUR1 Q9HB89 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30211613 0.94 OPRM1 (0.52) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL30321102 0.90 BDKRB2 (0.49) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL30321103 0.90 BDKRB2 (0.49) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL30211692 0.87 BDKRB2 (0.43) BDKRB2OPRM1OPRD1CAPN1NMUR2
SCHEMBL30211654 0.87 OPRM1 (0.46) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL30918517 0.84 OPRM1 (0.49) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL30918489 0.84 OPRM1 (0.49) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL30010846 0.84 NMUR2 (0.54) BDKRB2CAPN1NMUR2NMUR1
SCHEMBL29397180 0.81 OPRM1 (0.51) BDKRB2OPRM1OPRD1CAPN1GRB2
SCHEMBL29776901 0.80 GRB2 (0.53) BDKRB2OPRM1OPRD1CAPN1GRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285583-A1 LIQUID FORMULATION OF LONG-ACTING CONJUGATE OF GLUCAGON, GLP-1, AND GIP TRIGONAL AGONIST HANMI PHARM. CO., LTD. (KR) 2023-09-14 — — US claimed
EP-4154870-A1 LIQUID PREPARATION OF LONG-ACTING CONJUGATE OF GLUCAGON/GLP-1/GIP TRIGONAL AGONIST Hanmi Pharm. Co., Ltd. (KR) 2023-03-29 — — EP claimed
CN-115811970-A Liquid formulations of long-acting conjugates of glucagon, GLP-1 and GIP triple agonists 韩美药品株式会社 2023-03-17 — — CN claimed
US-20230285583-A1 LIQUID FORMULATION OF LONG-ACTING CONJUGATE OF GLUCAGON, GLP-1, AND GIP TRIGONAL AGONIST HANMI PHARM. CO., LTD. (KR) 2023-09-14 — — US disclosed
EP-4154870-A1 LIQUID PREPARATION OF LONG-ACTING CONJUGATE OF GLUCAGON/GLP-1/GIP TRIGONAL AGONIST Hanmi Pharm. Co., Ltd. (KR) 2023-03-29 — — EP disclosed
CN-115811970-A Liquid formulations of long-acting conjugates of glucagon, GLP-1 and GIP triple agonists 韩美药品株式会社 2023-03-17 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285583-A1 LIQUID FORMULATION OF LONG-ACTING CONJUGATE OF GLUCAGON, GLP-1, AND GIP TRIGONAL AGONIST GLP1R, GIPR, GCG BDKRB2 1142/4885OPRM1 1902/4885OPRD1 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback