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SCHEMBL30918517

SCHEMBL30918517

N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 5/20 0.49
▸ OPRD1 P41143 4/20 0.49
▸ BDKRB2 P30411 6/20 0.48
▸ CAPN1 P07384 6/20 0.43
▸ CTSB P07858 1/20 0.42
▸ GRB2 P62993 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30918489 1.00 OPRM1 (0.49) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL30321102 0.94 BDKRB2 (0.49) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL30321103 0.94 BDKRB2 (0.49) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL29576313 0.91 CAPN1 (0.47) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL30211613 0.90 OPRM1 (0.52) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL31669043 0.89 CAPN1 (0.47) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL30184771 0.87 OPRM1 (0.47) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL29595585 0.87 OPRM1 (0.47) OPRM1OPRD1BDKRB2CAPN1CTSB
SCHEMBL30918506 0.84 OPRM1 (0.45) OPRM1OPRD1BDKRB2CAPN1
SCHEMBL30211651 0.84 BDKRB2 (0.52) OPRM1OPRD1BDKRB2CAPN1GRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118159552-A Novel peptides as potent and selective GIP receptor agonists 赛诺菲 2024-06-07 — — CN claimed
CN-118159552-A Novel peptides as potent and selective GIP receptor agonists 赛诺菲 2024-06-07 — — CN disclosed
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