Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25093232 | 0.83 | NPC1 (0.41) | RECQLKMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL27812384 | 0.79 | ACACB (0.44) | ACACBACACAKMT2AALDH1A1MAPT | |
| SCHEMBL22065262 | 0.77 | DRD3 (0.47) | KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL26480953 | 0.74 | MAPT (0.48) | KMT2AALDH1A1TSHRLMNAMAPT | |
| SCHEMBL27812383 | 0.74 | L3MBTL1 (0.49) | ACACBKMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL28069735 | 0.74 | TDP1 (0.37) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL31680779 | 0.73 | PTGS2 (0.45) | ACACBACACAALDH1A1TSHRRAB9A | |
| Bicarbonate SCHEMBL9555855 | 0.72 | RAB9A (0.50) | ACACBACACARXRARXRBKMT2A | |
| SCHEMBL31680822 | 0.72 | P4HTM (0.41) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL18611555 | 0.71 | HRH3 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |