Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3820921 | 0.89 | HDAC8 (0.43) | CA2SMN1; SMN2GGPS1FDPSKCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL29252804 | 0.88 | KCNH2 (0.55) | CA2SMN1; SMN2GGPS1CNR2FDPS | |
| Fluoride Ion SCHEMBL30330501 | 0.88 | HDAC8 (0.42) | CA2SMN1; SMN2GGPS1FDPSKCNH2 | |
| Bromide SCHEMBL27897836 | 0.88 | HDAC8 (0.42) | CA2SMN1; SMN2GGPS1FDPSKCNH2 | |
| SCHEMBL30330020 | 0.84 | HDAC8 (0.40) | CA2SMN1; SMN2GGPS1FDPSKCNH2 | |
| SCHEMBL5818874 | 0.84 | TDP1 (0.47) | CA2GGPS1FDPSKCNH2 | |
| SCHEMBL29252367 | 0.84 | GGPS1 (0.48) | CA2SMN1; SMN2GGPS1CNR2FDFT1 | |
| SCHEMBL23004446 | 0.83 | FUT7 (0.47) | CA2GGPS1KCNH2 | |
| SCHEMBL29252424 | 0.83 | CA2 (0.51) | CA2SMN1; SMN2CNR2KCNH2FDFT1 | |
| SCHEMBL28734702 | 0.83 | HDAC8 (0.38) | CA2SMN1; SMN2GGPS1FDPSGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046704-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-30 | — | — | WO | disclosed |
| EP-4155723-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-29 | — | — | EP | disclosed |