Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MECP2 | P51608 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313886 | 1.00 | METAP2 (0.50) | METAP2ALDH1A1MEN1KDM4ELMNA | |
| SCHEMBL1646236 | 0.86 | GP6 (0.37) | METAP2ALDH1A1MEN1KMT2ACHEK1 | |
| SCHEMBL4831837 | 0.78 | HSD17B1 (0.53) | METAP2 | |
| SCHEMBL670668 | 0.78 | IDO1 (0.50) | METAP2ALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL5613019 | 0.78 | METAP2 (0.50) | METAP2 | |
| SCHEMBL13896466 | 0.78 | IDO1 (0.50) | MEN1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL7520387 | 0.78 | AKT1 (0.31) | — | |
| SCHEMBL917247 | 0.78 | IDO1 (0.46) | — | |
| SCHEMBL29899236 | 0.78 | IDO1 (0.50) | MEN1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL29746032 | 0.78 | IDO1 (0.50) | METAP2ALDH1A1MEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |