Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23569917 | 0.81 | HSD11B1 (0.49) | HSD11B1EGLN2GRM2ACHEMAP2 | |
| SCHEMBL1133108 | 0.80 | MAPK14 (0.47) | CYP3A4PTGS2ACHE | |
| SCHEMBL8974517 | 0.79 | KMO (0.42) | HSD11B1EGLN2PTGS2GRM2KMO | |
| SCHEMBL22760719 | 0.79 | ALDH1A1 (0.42) | HSD11B1EGLN2PTGS2GRM2KMO | |
| SCHEMBL21651103 | 0.79 | ESR2 (0.40) | HSD11B1CYP3A4PTGS2ACHEMAP2 | |
| SCHEMBL21513462 | 0.79 | GRM2 (0.45) | HSD11B1CYP3A4GRM2CRHR1HTR2B | |
| SCHEMBL23609094 | 0.78 | CYP3A4 (0.57) | CYP3A4CRHR1 | |
| SCHEMBL29974775 | 0.78 | CYP3A4 (0.57) | CYP3A4CRHR1 | |
| SCHEMBL21108846 | 0.77 | EGLN2 (0.42) | HSD11B1EGLN2CYP3A4GRM2KMO | |
| SCHEMBL23339896 | 0.77 | SLC6A2 (0.39) | HSD11B1EGLN2PTGS2GRM2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697974-A | Imidazole 3-oxide derivative based ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2023-02-03 | — | — | CN | disclosed |